We present a detailed characterization of coherence in seven transmon qubits in a circuit QED architecture. We find that spontaneous emission rates are strongly influenced by far off-resonant modes of the cavity and can be understood within a semiclassical circuit model. A careful analysis of the spontaneous qubit decay into a microwave transmission-line cavity can accurately predict the qubit lifetimes over two orders of magnitude in time and more than an octave in frequency. Coherence times T1 and T2* of more than a microsecond are reproducibly demonstrated.